python - urllib / sock.sendall(data) OSErrorで大きなファイル(約3GB)のアップロード

Question

環境: Mac OS X El Capitan / python 3.5.1

3GB程度のファイルをアップロードしたいです。

def read_in_chunks(file_object, chunk_size=4096):
    while True:
        data = file_object.read(chunk_size)
        if not data:
            break
        yield data

with open('3GB.mov', 'br') as f:
    data = b''.join([chunk for chunk in read_in_chunks(f)])

req = urllib.request.Request(url, data, headers)
response = urllib.request.urlopen(req)
the_page = response.read()

問題は ..

Traceback (most recent call last):
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/site-packages/requests/packages/urllib3/connectionpool.py", line 578, in urlopen
    chunked=chunked)
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/site-packages/requests/packages/urllib3/connectionpool.py", line 362, in _make_request
    conn.request(method, url, **httplib_request_kw)
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/http/client.py", line 1083, in request
    self._send_request(method, url, body, headers)
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/http/client.py", line 1128, in _send_request
    self.endheaders(body)
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/http/client.py", line 1079, in endheaders
    self._send_output(message_body)
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/http/client.py", line 913, in _send_output
    self.send(message_body)
  File "/Library/Frameworks/Python.framework/Versions/3.5/lib/python3.5/http/client.py", line 885, in send
    self.sock.sendall(data)
OSError: [Errno 22] Invalid argument

アドバイスをいただけますか？