It depends on the byte size that you're using. Knuth deliberately leaves the underlying implementation of bytes undefined - each byte can support anywhere from 64 to 100 underlying values, but the minimum is 64, and that's what most implementations seem to use.
Let's say each byte holds 64 values, and say you have the following register contents in rA:
+ 01 02 03 04 05
The least significant byte is on the right hand side. Therefore, the "overall" value of the entire rA register would be:
= (1 * 64^4) + (2 * 64^3) + (3 * 64^2) + (4 * 64^1) + (5 * 64^0)
= (1 * 16777216) + (2 * 262144) + (3 * 4096) + (4 * 64) + (5 * 1)
= 17314053
That's exactly what GNU MDK will give you:
MIX> weval 1(1:1),2(2:2),3(3:3),4(4:4),5(5:5)
+ 01 02 03 04 05 (0017314053)
For rAX (rA and rX considered as one register), it's the same idea, except you put rA to the left of rX. So if you have:
rA = + 01 02 03 04 05
rX = + 06 07 08 09 10
The overall value would be:
(1 * 64^9) + (2 * 64^8) + (3 * 64^7) + (4 * 64^6) + (5 * 64^5) +
(6 * 64^4) + (7 * 64^3) + (8 * 64^2) + (9 * 64^1) + (10 * 64^0)
For a decimal implementation, you would just use 100 instead of 64 as the base. So in the initial example, you would end up with:
= (1 * 100^4) + (2 * 100^3) + (3 * 100^2) + (4 * 100^1) + (5 * 100^0)
= 102030405
Hope that helps.